With OTRS it is not possibel, to run  one  VHost  and  have  e.g.  three
differnt targets like "abuse", "support" and "info" like

   http://support.customer1.com/abuse/
                               /info/
                               /support/
   http://support.customer2.com/abuse/
                               /info/
                               /support/

Why do you not think this is possible? And what will going to /abuse/ do? or /info/ or /support/? These aren't native to OTRS.
 
Also it is not possibel to have more then  one  customer  on  a  server,
because OTRS enforce to  use  ONE  database  instead  one  database  per
customer and target.

I don't understand this, either. Of course OTRS supports more than one customer. What does "support more than one customer" mean to you? 


You don't have to have an entirely different MySQL instance to run multiple instances of OTRS, either.

Further, why are you asking on the OTRS mailing list to tell you of another product?

If we can help, we'll try. If your mind is made up, I'm sure you can find something.

How, specifically, may we help you?