Hello,

I set up otrs on debian wheezy and it was working fine.
After sometime auto response mails stop working. 
When I check the system logs it gives the log

Sent no 'auto reply' for Ticket

I searched for this a lot, And found that x-loop header should not be mention
in mail filter for queue. I don't have x-loop header in mail filter queue.
I also found that this is not a error of otrs your mailing list is blocking of mail filter queue with x-loop header.

I don't have any x-loop header in mail filter queue. 
If this is not the problem in otrs then how it was working before and stop working
after sometime.
I am able to sent email notification manually editing responses.

Regards
Amit Bondwal