[otrs] IO Socket Error

I have OTRS in production on a Win32 platform. It has quit working and displays the error: IO::Socket::INET: connect: Unknown error at C:/otrs/otrs/Kernel/cpan-lib/CGI/Carp.pm line 301. I have tried restarting the services and the computer. Same thing. I have verified that both apache and mysql are running (I can connect to mysql through the phpmyadmin interface). Anybody know what this is about? Please, I am dead in the water. Thanks, Tyler Hepworth