[otrs] Using OTRS2.2 as a mail-only ticket handling system?

Hi all, I'd like to know if I can use otrs2.2 purely from my mailclient? Can it forward incoming messages in a way that I can just reply to them in my mailclient and otrs handles the handling and all? Currently, I can only find notifications, which give a lot of extra text that I do not want when replying. Anyone using otrs solely from their mail client (after setting up stuff in the webinterface, of course)? -- Gegroet, Tim