With OTRS auto reply we are facing strange problem.

we have 4 mailboxes for different businesses,we have auto-reply configured respectively for each mailbox.

cases are getting created when mails are sent to this 4 mailboxes,problem is auto response is going for single mailbox for all business ,though different mail are configured at Autresponse<->Queue

Is it something to do with SMTP setting where in we have Authenticated User id and Pwd for sending emails. 

Thanks in advance.

Regards

Ravi Shankar